Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295595 | 0.96 | HTT (0.45) | HTTTDP1L3MBTL1SMN1; SMN2FFAR1 | |
| SCHEMBL11299988 | 0.95 | HTT (0.46) | HTTTDP1L3MBTL1SMN1; SMN2FFAR1 | |
| SCHEMBL11298214 | 0.95 | HTT (0.46) | HTTTDP1L3MBTL1SMN1; SMN2FFAR1 | |
| SCHEMBL11298014 | 0.94 | HTT (0.47) | HTTTDP1L3MBTL1SMN1; SMN2FFAR1 | |
| SCHEMBL11300185 | 0.93 | HTT (0.48) | HTTTDP1L3MBTL1SMN1; SMN2FFAR1 | |
| SCHEMBL11296515 | 0.93 | HTT (0.48) | HTTTDP1L3MBTL1SMN1; SMN2FFAR1 | |
| SCHEMBL11302824 | 0.92 | HTT (0.42) | HTTTDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL11293779 | 0.92 | HTT (0.42) | HTTTDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL11290722 | 0.89 | MMP2 (0.40) | HTTTDP1L3MBTL1SMN1; SMN2FFAR1 | |
| SCHEMBL11297747 | 0.89 | HTT (0.44) | HTTTDP1L3MBTL1SMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356325-A | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-26 | — | — | US | disclosed |