Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294344 | 0.87 | CYP4F2 (0.43) | CYP4F2CYP4A11PPARGPPARANPC1 | |
| SCHEMBL11296820 | 0.81 | PPARG (0.41) | CYP4F2CYP4A11PPARGCYP2D6 | |
| SCHEMBL11299074 | 0.80 | PPARG (0.41) | CYP4F2CYP4A11PPARGNPC1LMNA | |
| SCHEMBL11295370 | 0.80 | KDM4E (0.30) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11295727 | 0.78 | F10 (0.31) | — | |
| SCHEMBL11295520 | 0.76 | HDAC8 (0.32) | — | |
| SCHEMBL11301530 | 0.76 | PPARA (0.38) | CYP4F2CYP4A11PPARGPPARANPC1 | |
| SCHEMBL11296832 | 0.75 | SLC7A5 (0.44) | CYP4F2CYP4A11PPARGNPC1LMNA | |
| SCHEMBL11297907 | 0.73 | PHGDH (0.30) | — | |
| SCHEMBL11301861 | 0.73 | GPR84 (0.33) | CYP4F2CYP4A11ALDH1A1HPGDCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261732-A | Alkyl and alkoxyalkyl N-3-alkyl and N-3,5-dialkylbenzoyl-N-isopropylaminoacetate herbicides | PPG INDUSTRIES, INC. (US) | 1981-04-14 | — | — | US | disclosed |