Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301244 | 0.92 | ESR1 (0.55) | ESR1ESR2MEN1KMT2ASIGMAR1 | |
| SCHEMBL10448023 | 0.88 | ESR1 (0.53) | ESR1ESR2MEN1KMT2ASIGMAR1 | |
| SCHEMBL8978824 | 0.88 | ESR1 (0.53) | ESR1ESR2MEN1KMT2ASIGMAR1 | |
| SCHEMBL4740369 | 0.88 | ESR1 (0.53) | ESR1ESR2MEN1KMT2ASIGMAR1 | |
| SCHEMBL7781763 | 0.86 | ESR1 (0.55) | ESR1ESR2MEN1KMT2ASIGMAR1 | |
| SCHEMBL8158952 | 0.84 | ESR1 (0.59) | ESR1ESR2MEN1KMT2ASIGMAR1 | |
| SCHEMBL5200056 | 0.84 | ESR1 (0.70) | ESR1ESR2 | |
| SCHEMBL8052267 | 0.84 | ESR1 (0.70) | ESR1ESR2 | |
| SCHEMBL17923963 | 0.82 | ESR1 (0.52) | ESR1ESR2MEN1KMT2ASIGMAR1 | |
| SCHEMBL8314216 | 0.82 | CHRM3 (0.38) | ESR1ESR2SIGMAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008796-B1 | POLYPHOSPHAZENE POLYMERS CONTAINING ALKOXY SUBSTITUENTS CONTAINING A FULLY SUBSTITUTED CARBON IN THE BETA POSITION AND PROCESS FOR THEIR PREPARATION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| US-4264759-A | Polyphosphazene polymers containing alkoxy substitutents containing a fully substituted carbon in the beta position | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| EP-0008796-A1 | Polyphosphazene polymers containing alkoxy substituents containing a fully substituted carbon in the beta position and process for their preparation | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-03-19 | — | — | EP | disclosed |