Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292531 | 0.90 | GAA (0.50) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11494234 | 0.85 | GAA (0.49) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11297831 | 0.83 | GAA (0.47) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11295074 | 0.82 | GAA (0.50) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL19407821 | 0.81 | GAA (0.50) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11294112 | 0.81 | GAA (0.47) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL2603374 | 0.80 | GAA (0.56) | GAAKMT2AMEN1HTTPKM | |
| SCHEMBL16426455 | 0.78 | GAA (0.54) | GAAKMT2AMEN1HTTPKM | |
| SCHEMBL17636821 | 0.78 | GAA (0.54) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| Butane SCHEMBL11489929 | 0.78 | GAA (0.59) | GAAKMT2AMEN1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006745-B1 | NITRO-CONTAINING ESTERS OF A SUBSTITUTED PHENYLPROPIONIC ACID, COMPOSITIONS CONTAINING THEM AS STABILIZING AGENT AGAINST OXIDATIVE DEGRADATION, AND STABILIZER COMPOSITIONS | UNIROYAL, INC. (US) | 1982-11-10 | — | — | EP | disclosed |
| EP-0006745-A1 | Nitro-containing esters of a substituted phenylpropionic acid, compositions containing them as stabilizing agent against oxidative degradation, and stabilizer compositions | UNIROYAL, INC. (US) | 1980-01-09 | — | — | EP | disclosed |
| US-4153597-A | STABILIZERS | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | disclosed |