Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494234 | 0.95 | GAA (0.49) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11294112 | 0.94 | GAA (0.47) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11494218 | 0.84 | ALDH1A1 (0.39) | GAAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11298586 | 0.83 | GAA (0.46) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11292531 | 0.83 | GAA (0.50) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11295074 | 0.83 | GAA (0.50) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11494223 | 0.83 | TDP1 (0.35) | GAAKMT2A | |
| SCHEMBL14508970 | 0.82 | GAA (0.52) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL17636821 | 0.82 | GAA (0.54) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL15342878 | 0.81 | GAA (0.53) | GAAKMT2AMEN1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006745-B1 | NITRO-CONTAINING ESTERS OF A SUBSTITUTED PHENYLPROPIONIC ACID, COMPOSITIONS CONTAINING THEM AS STABILIZING AGENT AGAINST OXIDATIVE DEGRADATION, AND STABILIZER COMPOSITIONS | UNIROYAL, INC. (US) | 1982-11-10 | — | — | EP | disclosed |
| US-4153597-A | STABILIZERS | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | disclosed |