Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 3/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11307329 | 0.91 | MAP2 (0.41) | MAP2GPR35IKBKBCHUKAKT1 | |
| SCHEMBL11306163 | 0.89 | MAP2 (0.52) | MAP2GPR35 | |
| SCHEMBL11297301 | 0.80 | MAP2 (0.48) | MAP2GPR35 | |
| SCHEMBL11259837 | 0.80 | CBFB (0.40) | MAP2GPR35 | |
| SCHEMBL11304667 | 0.79 | MEN1 (0.40) | MAP2GPR35IKBKB | |
| SCHEMBL11300066 | 0.79 | MAP2 (0.39) | MAP2GPR35IKBKBCHUKAKT1 | |
| SCHEMBL11305292 | 0.79 | MAP2 (0.54) | MAP2 | |
| SCHEMBL11298552 | 0.78 | MAP2 (0.49) | MAP2GPR35 | |
| SCHEMBL11300082 | 0.78 | MAP2 (0.62) | MAP2GPR35 | |
| SCHEMBL11304764 | 0.76 | MAP2 (0.42) | MAP2GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255442-A | 2-[(Methylsulfinyl)]-3-phenylindoles | SCHERING CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0000972-A2 | 2-Substituted-3-phenylindoles, their preparation, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-03-07 | — | — | EP | disclosed |