Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147956 | 0.92 | CA4 (0.36) | CA1CA4FAHD1 | |
| Bicarbonate SCHEMBL3044902 | 0.89 | CA4 (0.38) | CA1CA4FAHD1 | |
| Water SCHEMBL5969024 | 0.88 | CA1 (0.33) | CA1CA4FAHD1 | |
| SCHEMBL28005597 | 0.88 | CA1 (0.33) | CA1CA4FAHD1 | |
| SCHEMBL8420424 | 0.88 | CA1 (0.33) | CA1CA4FAHD1 | |
| SCHEMBL1445922 | 0.84 | CA4 (0.36) | CA1CA4FAHD1 | |
| SCHEMBL123336 | 0.84 | CA4 (0.36) | CA1CA4FAHD1 | |
| SCHEMBL8619595 | 0.84 | CA4 (0.36) | CA1CA4FAHD1 | |
| SCHEMBL22782 | 0.84 | — | — | |
| SCHEMBL23592 | 0.84 | CA4 (0.36) | CA1CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9402808-B2 | Liquid oral composition of lanthanum salts | PANACEA BIOTEC LIMITED (IN) | 2016-08-02 | — | — | US | claimed |
| US-20130302383-A1 | LIQUID ORAL COMPOSITION OF LANTHANUM SALTS | PANACEA BIOTEC PHARMA LIMITED (IN) | 2013-11-14 | — | — | US | claimed |
| WO-2012098562-A2 | LIQUID ORAL COMPOSITIONS OF LANTHANUM SALTS | PANACEA BIOTEC LIMITED (IN) | 2012-07-26 | — | — | WO | claimed |
| US-9402808-B2 | Liquid oral composition of lanthanum salts | PANACEA BIOTEC LIMITED (IN) | 2016-08-02 | — | — | US | disclosed |
| US-20130302383-A1 | LIQUID ORAL COMPOSITION OF LANTHANUM SALTS | PANACEA BIOTEC PHARMA LIMITED (IN) | 2013-11-14 | — | — | US | disclosed |
| WO-2012098562-A2 | LIQUID ORAL COMPOSITIONS OF LANTHANUM SALTS | PANACEA BIOTEC LIMITED (IN) | 2012-07-26 | — | — | WO | disclosed |