Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450805 | 1.00 | DNM1 (0.52) | DNM1TSHRRECQLGLAHPGD | |
| SCHEMBL9619197 | 1.00 | DNM1 (0.52) | DNM1TSHRRECQLGLAHPGD | |
| SCHEMBL6898223 | 0.96 | DNM1 (0.57) | DNM1TSHRRECQLGLAHPGD | |
| SCHEMBL11016989 | 0.96 | DNM1 (0.57) | DNM1TSHRRECQLGLAHPGD | |
| SCHEMBL4958512 | 0.96 | DNM1 (0.57) | DNM1TSHRRECQLGLAHPGD | |
| SCHEMBL2928217 | 0.96 | DNM1 (0.52) | DNM1TSHRRECQLGLAHPGD | |
| SCHEMBL4368365 | 0.93 | RECQL (0.46) | DNM1TSHRRECQLGLAHPGD | |
| SCHEMBL5804186 | 0.91 | RECQL (0.53) | DNM1TSHRRECQLGLAHPGD | |
| Tetrabuthylammonium SCHEMBL11225223 | 0.89 | RECQL (0.53) | DNM1TSHRRECQLGLAHPGD | |
| SCHEMBL10768788 | 0.88 | RECQL (0.44) | DNM1TSHRRECQLGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019226-B1 | PROCESS FOR PREPARING N-(ALPHA-ALKOXYETHYL)-CARBOXYLIC ACID AMIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-08-11 | — | — | EP | disclosed |
| EP-0019226-A1 | Process for preparing N-(alpha-alkoxyethyl)-carboxylic acid amides | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-26 | — | — | EP | disclosed |