Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.62 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488468 | 0.87 | OPRM1 (0.60) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL7488823 | 0.84 | CYP2D6 (0.60) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL5962492 | 0.84 | CHRM1 (0.64) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL319049 | 0.81 | CHRM1 (0.70) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL7491573 | 0.79 | OPRM1 (0.64) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL7489071 | 0.79 | OPRM1 (0.65) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL13081211 | 0.79 | OPRM1 (0.69) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL4152396 | 0.79 | CYP2D6 (0.70) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL14593660 | 0.79 | CHRM1 (0.68) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL13351318 | 0.79 | CHRM1 (0.68) | OPRM1OPRK1OPRL1CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338323-A | Piperidylbenzimidazolinone derivatives | SCIENCE UNION ET CIE (FR) | 1982-07-06 | — | — | US | disclosed |
| US-4264613-A | Piperidylbenzimidazolinone compounds | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1981-04-28 | — | — | US | disclosed |