Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.52 |
| ▸ | AR | P10275 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.46 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299214 | 1.00 | CYP19A1 (0.52) | CYP19A1ARLMNANR3C1PGR | |
| SCHEMBL11299210 | 1.00 | CYP19A1 (0.52) | CYP19A1ARLMNANR3C1PGR | |
| SCHEMBL11305366 | 0.92 | CYP19A1 (0.51) | CYP19A1ARLMNANR3C1PGR | |
| SCHEMBL11294656 | 0.92 | CYP19A1 (0.51) | CYP19A1ARLMNANR3C1PGR | |
| SCHEMBL11305361 | 0.92 | CYP19A1 (0.51) | CYP19A1ARLMNANR3C1PGR | |
| SCHEMBL11294657 | 0.92 | CYP19A1 (0.51) | CYP19A1ARLMNANR3C1PGR | |
| SCHEMBL11294655 | 0.92 | CYP19A1 (0.51) | CYP19A1ARLMNANR3C1PGR | |
| SCHEMBL11300356 | 0.86 | PGR (0.54) | ARLMNANR3C1PGRCYP3A4 | |
| SCHEMBL11300353 | 0.86 | PGR (0.54) | ARLMNANR3C1PGRCYP3A4 | |
| SCHEMBL11300351 | 0.86 | PGR (0.54) | ARLMNANR3C1PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361558-A | PREPARATION OF THESE ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |