Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27915712 | 0.74 | PDPK1 (0.46) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL2422995 | 0.71 | ADORA2A (0.41) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL3590212 | 0.71 | ALDH1A1 (0.42) | PDPK1PARP1MEN1KMT2AMAPT | |
| SCHEMBL29468124 | 0.70 | AXL (0.44) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL29368189 | 0.70 | AXL (0.44) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL31324910 | 0.70 | AXL (0.44) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL29631094 | 0.70 | AXL (0.44) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL29365402 | 0.70 | AXL (0.53) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL21393430 | 0.70 | AXL (0.44) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL4037241 | 0.70 | AXL (0.44) | PDPK1PARP1AXLMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359420-A | HYPOTENSIVE AGENT, MUSCLE RELAXANTS | HOFFMANN-LA ROCHE INC. (US) | 1982-11-16 | — | — | US | disclosed |