Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073033 | 0.78 | — | — | |
| SCHEMBL13454914 | 0.71 | METAP2 (0.33) | CHRM2CHRM1CHRM4CHRM3PTGS2 | |
| SCHEMBL13454915 | 0.71 | METAP2 (0.33) | CHRM2CHRM1CHRM4CHRM3PTGS2 | |
| SCHEMBL25821850 | 0.69 | CA12 (0.35) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL9608756 | 0.69 | CA12 (0.35) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL14734513 | 0.67 | CHRM2 (0.37) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL23871861 | 0.67 | RET (0.38) | HSD11B1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL29308963 | 0.67 | CHRM2 (0.38) | HSD11B1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL24119155 | 0.67 | CHRM2 (0.34) | HSD11B1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL2457612 | 0.66 | CHRM2 (0.43) | CHRM2CHRM1CHRM4CHRM3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56030940-A | — | — | None | — | — | JP | disclosed |
| JP-S5630940-A | MONOTERPENOID COMPOUND | MITSUBISHI CHEM IND LTD | 1981-03-28 | — | — | JP | disclosed |