Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299463 | 0.80 | CYP17A1 (0.47) | PRKCACYP17A1CYP19A1MAPTALDH1A1 | |
| SCHEMBL20730932 | 0.78 | CYP17A1 (0.50) | PRKCACYP17A1CYP19A1MAPTALDH1A1 | |
| SCHEMBL8489888 | 0.78 | PRKCA (0.46) | PRKCACYP17A1CYP19A1MAPTALDH1A1 | |
| SCHEMBL1322672 | 0.75 | PRKCA (0.44) | PRKCACYP17A1CYP19A1MAPTALDH1A1 | |
| SCHEMBL10532688 | 0.74 | CYP17A1 (0.53) | PRKCACYP17A1CYP19A1MAPTALDH1A1 | |
| SCHEMBL28267986 | 0.74 | CYP17A1 (0.47) | PRKCACYP17A1CYP19A1MAPTALDH1A1 | |
| SCHEMBL16731832 | 0.73 | CYP17A1 (0.55) | PRKCACYP17A1CYP19A1MAPTALDH1A1 | |
| SCHEMBL27437173 | 0.73 | CYP17A1 (0.51) | PRKCACYP17A1CYP19A1MAPTALDH1A1 | |
| SCHEMBL19475250 | 0.72 | CYP17A1 (0.54) | PRKCACYP17A1CYP19A1MAPTALDH1A1 | |
| SCHEMBL10618169 | 0.72 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032905-A4 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS. | FOLEY WILLIAM M JUN | 1981-08-27 | — | — | EP | disclosed |
| EP-0032905-A1 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS | FOLEY, Jr., William M. (US) | 1981-08-05 | — | — | EP | disclosed |
| WO-1980002840-A1 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS | FOLEY W | 1980-12-24 | — | — | WO | disclosed |