SCHEMBL11299884

SCHEMBL11299884

CC(C)C(C(=O)O)(C(C)C=C(Cl)Cl)C(NS)c1cc2ccccc2c(Oc2ccccc2)n1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NR2E3 Q9Y5X4 1/20 0.33
EGLN2 Q96KS0 5/20 0.31
MAPK8 P45983 1/20 0.31
EGLN1 Q9GZT9 2/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11307854 0.85 BRAF (0.34) MEN1KMT2AEGLN2EGLN1LMNA
SCHEMBL11272213 0.84 ALDH1A1 (0.33) MEN1KMT2ANR2E3EGLN2EGLN1
SCHEMBL11307347 0.84 ALDH1A1 (0.32) MEN1KMT2AEGLN2EGLN1LMNA
SCHEMBL11304929 0.81 MEN1 (0.33) MEN1KMT2ANR2E3MAPK8
SCHEMBL11335209 0.80 PTGS1 (0.45) MEN1KMT2ALMNA
SCHEMBL11268086 0.74 MEN1 (0.33) MEN1KMT2ANR2E3EGLN2MAPK8
SCHEMBL11332930 0.73 PTGS1 (0.44) MEN1KMT2ALMNA
SCHEMBL11275495 0.73 EGLN2 (0.33) KMT2AEGLN2EGLN1LMNA
SCHEMBL11326187 0.71 PTGS1 (0.44) MEN1KMT2ALMNA
SCHEMBL11276788 0.71 SMN1; SMN2 (0.34) EGLN2EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4338326-A PESTICIDES UNION CARBIDE CORPORATION (US) 1982-07-06 US disclosed