Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.71 |
| ▸ | SQLE | Q14534 | 5/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310163 | 1.00 | KMT2A (0.71) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11301036 | 1.00 | KMT2A (0.71) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11310161 | 1.00 | KMT2A (0.71) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL1301873 | 0.87 | KMT2A (0.56) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL1301876 | 0.87 | KMT2A (0.56) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL1301879 | 0.87 | KMT2A (0.56) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Farnesol SCHEMBL3052544 | 0.85 | KMT2A (0.83) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Geranylgeraniol SCHEMBL23814969 | 0.84 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL7944378 | 0.84 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Farnesol SCHEMBL7546574 | 0.84 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260551-A | ALIPHATIC OR AROMATIC ESTERS, ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1981-04-07 | — | — | US | disclosed |
| US-4192953-A | TREATMENT OF PEPTIC ULCERS | SANKYO COMPANY LIMITED (JP) | 1980-03-11 | — | — | US | disclosed |
| US-4059641-A | ANTIULCER | SANKYO COMPANY LIMITED (JA) | 1977-11-22 | — | — | US | disclosed |