Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | EPOR | P19235 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | GLI1 | P08151 | 1/20 | 0.33 |
| ▸ | GLI2 | P10070 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306956 | 0.91 | TDP1 (0.44) | TDP1ALDH1A1PTGS1MEN1CYP2D6 | |
| SCHEMBL11300851 | 0.90 | TDP1 (0.46) | TDP1ALDH1A1PTGS1MEN1CYP2D6 | |
| SCHEMBL11302282 | 0.89 | TDP1 (0.45) | TDP1ALDH1A1PTGS1MEN1CYP2D6 | |
| SCHEMBL11305007 | 0.89 | TDP1 (0.46) | TDP1ALDH1A1PTGS1MEN1CYP2D6 | |
| SCHEMBL11301973 | 0.89 | TDP1 (0.46) | TDP1ALDH1A1PTGS1MEN1CYP2D6 | |
| SCHEMBL11303512 | 0.87 | TDP1 (0.45) | TDP1ALDH1A1PTGS1MEN1CYP2D6 | |
| SCHEMBL11299862 | 0.86 | TDP1 (0.44) | TDP1ALDH1A1PTGS1MEN1CYP2D6 | |
| SCHEMBL11312538 | 0.86 | ALDH1A1 (0.44) | TDP1ALDH1A1PTGS1MEN1CYP2D6 | |
| SCHEMBL11306511 | 0.85 | ALDH1A1 (0.44) | TDP1ALDH1A1PTGS1MEN1CYP2D6 | |
| SCHEMBL11305606 | 0.85 | PTGS1 (0.41) | TDP1ALDH1A1PTGS1MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4291057-A | INSECTICIDES AND MITICIDES | UNION CARBIDE CORPORATION (US) | 1981-09-22 | — | — | US | disclosed |