Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571222 | 0.92 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL1790807 | 0.88 | CA1 (0.68) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| Ethyl Acetate SCHEMBL11299570 | 0.87 | ELANE (0.53) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL13410648 | 0.87 | MEN1 (0.64) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL14019810 | 0.87 | MEN1 (0.64) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL27550906 | 0.86 | CA1 (0.66) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11306462 | 0.85 | ELANE (0.51) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| Ethyl Benzoate SCHEMBL25388294 | 0.84 | LMNA (0.70) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| Ethyl Benzoate SCHEMBL55674 | 0.84 | LMNA (0.70) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL6788089 | 0.84 | CA1 (0.73) | SMN1; SMN2RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005530-B1 | NEW MERCAPTOPHENYLKETONES AND THEIR USE AS INITIATORS FOR THE PHOTOPOLYMERISATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |
| US-4279721-A | Mercaptophenyl ketones as initiators for the photopolymerization of ethylenically unsaturated compounds | CIBA-GEIGY CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |
| EP-0005530-A1 | New mercaptophenylketones and their use as initiators for the photopolymerisation of ethylenically unsaturated compounds | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | disclosed |