⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300171 | 1.00 | — | — | |
| SCHEMBL2049797 | 1.00 | — | — | |
| SCHEMBL10768180 | 0.71 | — | — | |
| SCHEMBL157367 | 0.68 | — | — | |
| SCHEMBL9387479 | 0.68 | — | — | |
| SCHEMBL11215030 | 0.68 | — | — | |
| SCHEMBL14373983 | 0.66 | — | — | |
| SCHEMBL11258439 | 0.65 | — | — | |
| SCHEMBL23796481 | 0.64 | — | — | |
| SCHEMBL20617897 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4131614-A | Process for preparing cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1978-12-26 | — | — | US | claimed |
| EP-0004753-B1 | PREPARATION OF TETRAHYDROBENZOXOCINS AND CIS-HEXAHYDRODIBENZOPYRANONES | ELI LILLY AND COMPANY (US) | 1982-05-26 | — | — | EP | disclosed |
| EP-0004753-A1 | Preparation of tetrahydrobenzoxocins and cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-17 | — | — | EP | disclosed |
| EP-0004753-A1 | Preparation of tetrahydrobenzoxocins and cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-17 | — | — | EP | disclosed |
| US-4171315-A | Preparation of cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-16 | — | — | US | disclosed |
| US-4171315-A | Preparation of cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-16 | — | — | US | disclosed |
| US-4148809-A | Process for preparing dl-cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones | ELI LILLY AND COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4140701-A | 2,6-Methano-2H-1-benzoxocins | ELI LILLY AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |
| US-4133816-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4131614-A | Process for preparing cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4131614-A | Process for preparing cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4131614-A | Process for preparing cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4115403-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo [b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4054582-A | Process for converting cis-hexahydrodibenzo[b,d]pyran-9-ones to trans-hexahydrodibenzo[b,d]-pyran-9-ones | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054581-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |