⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301400 | 1.00 | — | — | |
| SCHEMBL11300171 | 1.00 | — | — | |
| SCHEMBL10768180 | 0.71 | — | — | |
| SCHEMBL157367 | 0.68 | — | — | |
| SCHEMBL9387479 | 0.68 | — | — | |
| SCHEMBL11215030 | 0.68 | — | — | |
| SCHEMBL14373983 | 0.66 | — | — | |
| SCHEMBL11258439 | 0.65 | — | — | |
| SCHEMBL23796481 | 0.64 | — | — | |
| SCHEMBL20617897 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258322-B2 | Synthesis of hexahydrodibenzopyranones | WATSON LABORATORIES, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258322-B2 | Synthesis of hexahydrodibenzopyranones | WATSON LABORATORIES, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| CN-102131795-A | Improved synthesis of hexahydrodibenzopyranones | DALTON CHEMICAL LAB INC | 2011-07-20 | — | — | CN | disclosed |
| EP-2331519-A1 | IMPROVED SYNTHESIS OF HEXAHYDRODIBENZOPYRANONES | Watson Laboratories, Inc. (US) | 2011-06-15 | — | — | EP | disclosed |
| US-20100056811-A1 | Synthesis of Hexahydrodibenzopyranones | WATSON LABORATORIES, INC. | 2010-03-04 | — | — | US | disclosed |
| US-20100056811-A1 | Synthesis of Hexahydrodibenzopyranones | WATSON LABORATORIES, INC. | 2010-03-04 | — | — | US | disclosed |
| WO-2010022520-A1 | IMPROVED SYNTHESIS OF HEXAHYDRODIBENZOPYRANONES | DALTON CHEMICAL LABORATORIES INC. (CA) | 2010-03-04 | — | — | WO | disclosed |
| EP-0096480-B1 | PREPARATION OF 6A, 10A-TRANS-HEXAHYDRODIBENZOPYRANONES | ELI LILLY AND COMPANY (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0096480-A2 | Preparation of 6a, 10a-trans-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1983-12-21 | — | — | EP | disclosed |
| US-4395560-A | Preparation of 6a,10a-trans-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1983-07-26 | — | — | US | disclosed |
| US-4088777-A | Hexahydro-dibenzo[b,d]pyran-9-ones as anticonvulsant drugs | ELI LILLY AND COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4087547-A | Hexahydro-dibenzo[b,d]pyran-9-ones in treatment of glaucoma | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4087545-A | Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4087546-A | Hexahydro-dibenzo[b,d]pyran-9-ones as antiasthmatic drugs | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4075230-A | Preparation of optically active trans-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4054583-A | Process for converting 2,7-dihydroxy-5-isopropylidene-9-substituted-2,6-methano-3,4,5,6-tetrahydro-2H-1-benzoxocin to trans-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo(b,d)pyran-9-one | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054581-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-3987188-A | Hexahydro-dibenzo[b,d]pyran-9-ones as sedative drugs | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3953603-A | Hexahydro-dibenzo[b,d,]pyran-9-ones as psychotropic, particularly anti-depressant drugs | ELI LILLY AND COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
| US-3944673-A | Hexahydro-dibenzo[b,d]pyran-9-ones as analgesic drugs | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | disclosed |