Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297720 | 0.88 | ANPEP (0.38) | MMP1MMP2MMP3ANPEP | |
| SCHEMBL11296860 | 0.84 | ANPEP (0.32) | MMP1MMP2MMP3ANPEP | |
| SCHEMBL11299593 | 0.83 | S1PR2 (0.44) | ANPEP | |
| SCHEMBL11306049 | 0.82 | KDM4E (0.32) | — | |
| SCHEMBL11307612 | 0.82 | ANPEP (0.32) | MMP1MMP2MMP3ANPEP | |
| SCHEMBL11303958 | 0.80 | — | — | |
| SCHEMBL1582657 | 0.79 | CTSC (0.40) | MMP1MMP2MMP3ANPEP | |
| SCHEMBL11298100 | 0.78 | MEN1 (0.44) | MMP1MMP3ANPEP | |
| SCHEMBL11303917 | 0.78 | DPP7 (0.34) | MMP2ANPEP | |
| SCHEMBL1582304 | 0.77 | CTSC (0.34) | ANPEPTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026409-A1 | Combinations of active ingredients, pharmaceutical preparations, as well as their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-08 | — | — | EP | disclosed |
| US-4250085-A | PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |