Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 8/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297720 | 0.89 | ANPEP (0.38) | ANPEPFNTAFNTB | |
| SCHEMBL11301401 | 0.83 | MMP1 (0.32) | ANPEP | |
| SCHEMBL20521898 | 0.77 | FAAH (0.56) | EPHX1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL11296860 | 0.77 | ANPEP (0.32) | ANPEP | |
| SCHEMBL11306049 | 0.76 | KDM4E (0.32) | — | |
| SCHEMBL11303958 | 0.73 | — | — | |
| SCHEMBL1582657 | 0.72 | CTSC (0.40) | ANPEP | |
| SCHEMBL11298100 | 0.72 | MEN1 (0.44) | ANPEPMEN1KMT2AGAA | |
| SCHEMBL11303917 | 0.71 | DPP7 (0.34) | ANPEPERAP2 | |
| SCHEMBL11298731 | 0.71 | S1PR2 (0.33) | S1PR2S1PR1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250085-A | PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |