Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352154 | 0.88 | ALDH1A1 (0.48) | RAB9ALMNAHTTSMN1; SMN2OPRL1 | |
| Hydrochloric Acid SCHEMBL11305184 | 0.82 | KDM4E (0.42) | LMNAPOLBHTTHSD17B10KMT2A | |
| SCHEMBL7357138 | 0.82 | ALDH1A1 (0.41) | RAB9APOLBSMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL7353697 | 0.81 | SCN10A (0.36) | SCN10A | |
| Hydrochloric Acid SCHEMBL11305461 | 0.81 | ALDH1A1 (0.40) | RAB9APOLBSMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL7357211 | 0.81 | SCN10A (0.33) | SCN10A | |
| SCHEMBL7347934 | 0.80 | CYP1A2 (0.52) | RAB9ALMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL7354966 | 0.78 | SMN1; SMN2 (0.43) | LMNAPOLBHTTSMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL11309714 | 0.77 | SCN10A (0.39) | LMNAHTTSMN1; SMN2HSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL11306270 | 0.77 | SCN10A (0.37) | LMNAHSD17B10KMT2ASCN10ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361563-A | CARDIOTONIC, ANTITHROMBOTIC | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-11-30 | — | — | US | disclosed |