Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486778 | 0.87 | MEN1 (0.48) | MEN1KMT2APOLBATMALDH1A1 | |
| SCHEMBL10488605 | 0.79 | POLB (0.44) | MEN1KMT2AGAAPOLBATM | |
| SCHEMBL6529128 | 0.74 | — | — | |
| SCHEMBL11788093 | 0.73 | ALDH1A1 (0.36) | MEN1KMT2AATMALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11302629 | 0.70 | — | — | |
| SCHEMBL11251838 | 0.67 | CYP2D6 (0.33) | — | |
| SCHEMBL10861324 | 0.67 | KDM4E (0.37) | POLBALDH1A1 | |
| SCHEMBL11032929 | 0.65 | — | — | |
| SCHEMBL1993072 | 0.65 | — | — | |
| SCHEMBL7918442 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258181-A | BACTERICIDES, AMTITUMOR AGENTS, ANTICARCINOGENIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-24 | — | — | US | disclosed |