Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187910 | 0.81 | SMN1; SMN2 (0.43) | TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL661763 | 0.81 | SMN1; SMN2 (0.43) | TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL490446 | 0.81 | SMN1; SMN2 (0.43) | TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5606099 | 0.80 | SMN1; SMN2 (0.39) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL15722793 | 0.75 | TSHR (0.42) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL18339318 | 0.70 | TSHR (0.46) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL995740 | 0.70 | — | — | |
| SCHEMBL50447 | 0.70 | — | — | |
| SCHEMBL4867613 | 0.70 | — | — | |
| SCHEMBL30415488 | 0.70 | SMN1; SMN2 (0.39) | TSHRSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4246186-A | RHODIUM HYDROGENATION CATALYST | UNION CARBIDE CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |