⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4867613 | 1.00 | — | — | |
| SCHEMBL30415488 | 1.00 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL7668341 | 0.81 | — | — | |
| SCHEMBL4188929 | 0.79 | — | — | |
| SCHEMBL661763 | 0.79 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL4382224 | 0.79 | ALDH1A1 (0.40) | — | |
| SCHEMBL12890924 | 0.79 | — | — | |
| SCHEMBL11259359 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL27757806 | 0.79 | — | — | |
| SCHEMBL27528410 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2076 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118175990-A | Osmotic formulation composition comprising an acid sensitive ingredient | 奥德森生物有限公司 | 2024-06-11 | — | — | CN | claimed |
| US-8980319-B2 | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans | MALLINCKRODT LLC (US) | 2015-03-17 | — | — | US | claimed |
| US-20140086987-A1 | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans | MALLINCKRODT LLC (US) | 2014-03-27 | — | — | US | claimed |
| US-8597681-B2 | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans | MALLINCKRODT LLC (US) | 2013-12-03 | — | — | US | claimed |
| US-8529955-B2 | Methods of treatment using a gastric retained gabapentin dosage | DEPOMED, INC. (US) | 2013-09-10 | — | — | US | claimed |
| US-8440232-B2 | Methods of treatment using a gastric retained gabapentin dosage | DEPOMED, INC. (US) | 2013-05-14 | — | — | US | claimed |
| CN-102697704-A | Controlled release formulations of opioid and nonopioid analgesics | ALZA CORP | 2012-10-03 | — | — | CN | claimed |
| US-20120064168-A1 | METHODS OF TREATMENT USING A GASTRIC RETAINED GABEPENTIN DOSAGE | DEPOMED, INC. (US) | 2012-03-15 | — | — | US | claimed |
| US-8119166-B2 | Methods of treatment using a gastric retained gabapentin dosage | DEPOMED, INC. (US) | 2012-02-21 | — | — | US | claimed |
| US-20120027823-A1 | METHODS OF TREATMENT USING A GASTRIC RETAINED GABAPENTIN DOSAGE | DEPOMED, INC. (US) | 2012-02-02 | — | — | US | claimed |
| US-5990324-A | Process for producing 3-methyltetrahydrofuran | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1999-11-23 | — | — | US | claimed |
| EP-0869125-A1 | Process for producing 3-methyltetrahydrofuran | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1998-10-07 | — | — | EP | claimed |
| EP-0589314-B1 | Process for the preparation of 2-methyl-1,4-butanediol and 3-methyltetrahydrofuran | BASF AG (DE) | 1997-01-22 | — | — | EP | claimed |
| US-5536854-A | Preparation of 2-methyl-1,4-butanediol and 3-methyltetrahydrofuran | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-16 | — | — | US | claimed |
| US-5458887-A | OF AN OSMOTIC CORE CONTAINING A DRUG AND A WATER SWELLABLE COMPONENT AND A WATER RESISTANT POLYMER COATING CONTAINING A COMPOUND WHICH DISSOLVES IN GASTROINTESTINAL FLUID | ANDRX PHARMACEUTICALS, INC. (US) | 1995-10-17 | — | — | US | claimed |
| EP-0359042-B1 | Process for the isolation of 2-keto-polyhydroxy-C6-carboxylic acids, especially 2-keto-L-gulonic acid, from aqueous fermentation media | BASF AG (DE) | 1995-02-01 | — | — | EP | claimed |
| EP-0589314-A1 | Process for the preparation of 2-methyl-1,4-butanediol and 3-methyltetrahydrofuran | BASF Aktiengesellschaft (DE) | 1994-03-30 | — | — | EP | claimed |
| EP-0403993-B1 | PROCESS FOR THE PREPARATION OF SODIUM OR POTASSIUM L-ASCORBATE | ENCO ENG AG (CH) | 1992-09-23 | — | — | EP | claimed |
| EP-0326727-A1 | Sustained release implant and method for preparing same | INTERNATIONAL MINERALS AND CHEMICAL CORPORATION (US) | 1989-08-09 | — | — | EP | claimed |
| US-4761289-A | Sustained release implant and method for preparing same | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1988-08-02 | — | — | US | claimed |