Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11165965 | 0.92 | MCHR1 (0.55) | MCHR1CHRM1HTR2ACYP2D6POLB | |
| SCHEMBL10356773 | 0.92 | MCHR1 (0.55) | MCHR1CHRM1HTR2ACYP2D6POLB | |
| SCHEMBL11165531 | 0.92 | MCHR1 (0.55) | MCHR1CHRM1HTR2ACYP2D6POLB | |
| SCHEMBL11441498 | 0.91 | MCHR1 (0.56) | MCHR1CHRM1HTR2ACYP2D6POLB | |
| SCHEMBL11178712 | 0.87 | POLB (0.55) | MCHR1CHRM1HTR2ACYP2D6POLB | |
| SCHEMBL11188865 | 0.86 | POLB (0.56) | MCHR1CHRM1HTR2ACYP2D6POLB | |
| SCHEMBL11196583 | 0.85 | MCHR1 (0.53) | MCHR1CHRM1HTR2ACYP2D6LMNA | |
| SCHEMBL11200220 | 0.83 | POLB (0.54) | POLBLMNAMAPT | |
| SCHEMBL11194691 | 0.83 | POLB (0.52) | MCHR1CHRM1HTR2ACYP2D6POLB | |
| SCHEMBL11198118 | 0.83 | POLB (0.54) | MCHR1POLBMAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |