Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11178712 | 0.91 | POLB (0.55) | POLBHSD17B10TSHRKDM4EGAA | |
| SCHEMBL11200220 | 0.89 | POLB (0.54) | POLBHSD17B10TSHREGFRCDK2 | |
| SCHEMBL10356773 | 0.87 | MCHR1 (0.55) | POLBHSD17B10TSHRCNR1MAPT | |
| SCHEMBL11165965 | 0.87 | MCHR1 (0.55) | POLBHSD17B10TSHRCNR1MAPT | |
| SCHEMBL11194691 | 0.87 | POLB (0.52) | POLBHSD17B10TSHRKDM4EGAA | |
| SCHEMBL11165531 | 0.87 | MCHR1 (0.55) | POLBHSD17B10TSHRCNR1MAPT | |
| SCHEMBL11441498 | 0.86 | MCHR1 (0.56) | POLBGAACNR1MAPTMCHR1 | |
| SCHEMBL11442018 | 0.85 | ALDH1A1 (0.55) | POLBHSD17B10TSHRKDM4EGAA | |
| SCHEMBL11173931 | 0.84 | POLB (0.49) | POLBHSD17B10TSHRKDM4EGAA | |
| SCHEMBL11302230 | 0.83 | MCHR1 (0.60) | POLBCNR1MAPTMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | claimed |
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |