SCHEMBL11304166

SCHEMBL11304166

C=C(C)C(=O)Oc1ccc(C(=O)O)cc1[C@H](CC)c1cccc(N(C(C)C)C(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 0.40
TSHR P16473 3/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
GAA P10253 2/20 0.40
RAB9A P51151 1/20 0.40
ELANE P08246 1/20 0.37
HTT P42858 2/20 0.34
CHRM2 P08172 2/20 0.34
CHRM1 P11229 2/20 0.34
LMNA P02545 2/20 0.34
MEN1 O00255 1/20 0.34
ABCC4 O15439 1/20 0.34
USP2 O75604 1/20 0.34
TP53 P04637 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
ADORA3 P0DMS8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11292328 1.00 TTR (0.40) TTRTSHRALDH1A1KDM4EGAA
SCHEMBL724698 0.88 CHRM2 (0.45) TTRTSHRALDH1A1KDM4EGAA
SCHEMBL11297464 0.87 CHRM2 (0.48) ELANECHRM2CHRM1
SCHEMBL11300770 0.86 CHRM2 (0.33) ALDH1A1KDM4EGAARAB9AELANE
SCHEMBL19212506 0.83 KDM4E (0.40) TTRTSHRALDH1A1KDM4EGAA
SCHEMBL723430 0.82 MRGPRX4 (0.48) RAB9ATP53MAPTPKMHPGD
SCHEMBL3960558 0.82 MRGPRX4 (0.48) RAB9ATP53MAPTPKMHPGD
Hydrochloric Acid SCHEMBL723194 0.81 MRGPRX4 (0.47) RAB9ATP53MAPTPKMHPGD
Hydrochloric Acid SCHEMBL1354482 0.81 MRGPRX4 (0.47) RAB9ATP53MAPTPKMHPGD
SCHEMBL6473873 0.80 HSP90AA1 (0.41) TTRALDH1A1KDM4EGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012098560-A2 PROCESS FOR THE PREPARATION OF MUSCARINIC RECEPTOR ANTAGONIST MSN LABORATORIES LIMITED (IN) 2012-07-26 WO claimed
WO-2012098560-A2 PROCESS FOR THE PREPARATION OF MUSCARINIC RECEPTOR ANTAGONIST MSN LABORATORIES LIMITED (IN) 2012-07-26 WO disclosed