Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412379 | 0.84 | CHRM1 (0.54) | CHRM2CHRM5CHRM1CHRM3HRH1 | |
| SCHEMBL3721172 | 0.84 | CHRM1 (0.54) | CHRM2CHRM5CHRM1CHRM3HRH1 | |
| SCHEMBL724698 | 0.82 | CHRM2 (0.45) | CHRM2CHRM1TTRMAPTESR1 | |
| SCHEMBL2431819 | 0.82 | ALDH1A1 (0.40) | CHRM2CHRM5CHRM1CHRM3HRH1 | |
| SCHEMBL722593 | 0.81 | CHRM3 (0.38) | CHRM2CHRM5CHRM1CHRM3HRH1 | |
| SCHEMBL2167352 | 0.81 | CHRM3 (0.38) | CHRM2CHRM5CHRM1CHRM3HRH1 | |
| SCHEMBL7752284 | 0.81 | CHRM3 (0.38) | CHRM2CHRM5CHRM1CHRM3HRH1 | |
| SCHEMBL11292328 | 0.80 | TTR (0.40) | HSP90AA1HSP90AB1CHRM2CHRM1TTR | |
| SCHEMBL723430 | 0.80 | MRGPRX4 (0.48) | MAPTRXRAPOLBSMN1; SMN2HPGD | |
| SCHEMBL3960558 | 0.80 | MRGPRX4 (0.48) | MAPTRXRAPOLBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858650-B1 | For therapy of urinary incontinence | SCHWARZ PHARMA AG (DE) | 2005-02-22 | — | — | US | disclosed |