Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274123 | 0.80 | MAPT (0.52) | MC4RMAPTKMT2AHSD17B10TSHR | |
| SCHEMBL29980612 | 0.78 | KMT2A (0.55) | MC4RMAPTKMT2AHSD17B10TSHR | |
| SCHEMBL1141274 | 0.76 | GAA (0.56) | MC4RMAPTKMT2AHSD17B10TSHR | |
| SCHEMBL15210472 | 0.76 | MAPT (0.61) | MC4RMAPTKMT2AHSD17B10TSHR | |
| SCHEMBL16827248 | 0.75 | MAPT (0.56) | MC4RMAPTKMT2AHSD17B10TSHR | |
| SCHEMBL1880439 | 0.75 | MC4R (1.00) | MC4RMAPTKMT2AHSD17B10GAA | |
| SCHEMBL1654688 | 0.75 | HSD17B10 (1.00) | MAPTKMT2AHSD17B10TSHRGAA | |
| Lithium SCHEMBL7065338 | 0.74 | GAA (0.55) | MC4RMAPTKMT2AHSD17B10TSHR | |
| SCHEMBL1726035 | 0.74 | GAA (0.55) | MC4RMAPTKMT2AHSD17B10TSHR | |
| Potassium SCHEMBL7063916 | 0.74 | GAA (0.55) | MC4RMAPTKMT2AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007402-B1 | 2-OXO AND 2-THIOXO-1,3-DITHIOLE COMPOUNDS, THEIR PREPARATION AND USE AND PLANT METABOLISM REGULATING AGENTS COMPRISING THEM | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |
| US-4265655-A | ESTER-SUBSTITUTED 1,3-DITHIOLANES | CIBA-GEIGY CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
| EP-0007402-A1 | 2-Oxo and 2-thioxo-1,3-dithiole compounds, their preparation and use and plant metabolism regulating agents comprising them | CIBA-GEIGY AG (CH) | 1980-02-06 | — | — | EP | disclosed |