Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.45 |
| ▸ | CDC7 | O00311 | 2/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1141274 | 0.98 | GAA (0.56) | GAAKMT2AHSD17B10MAPTNPC1 | |
| Potassium SCHEMBL7063916 | 0.96 | GAA (0.55) | GAAKMT2AHSD17B10MAPTNPC1 | |
| SCHEMBL1726035 | 0.96 | GAA (0.55) | GAAKMT2AHSD17B10MAPTNPC1 | |
| SCHEMBL14650156 | 0.90 | ALDH1A1 (0.51) | GAAKMT2AHSD17B10MAPTNPC1 | |
| SCHEMBL6206616 | 0.90 | ALDH1A1 (0.54) | GAAKMT2AHSD17B10MAPTNPC1 | |
| SCHEMBL13359464 | 0.88 | GAA (0.49) | GAAKMT2AHSD17B10MAPTNPC1 | |
| SCHEMBL10925924 | 0.88 | MAPT (0.56) | GAAKMT2AHSD17B10MAPTNPC1 | |
| Protiofate SCHEMBL871311 | 0.81 | MAPT (0.50) | GAAKMT2AHSD17B10MAPTALDH1A1 | |
| SCHEMBL11099233 | 0.80 | ALDH1A1 (0.48) | GAAKMT2AHSD17B10MAPTNPC1 | |
| SCHEMBL15210472 | 0.80 | MAPT (0.61) | GAAKMT2AHSD17B10MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608164-B2 | Diaryl carbonate reacted with dihydroxy aromatic compounds in the presence of a transesterification catalyst; furan diol derivative is dimethyl 3,4-dihydroxy-2,5-furandiacarboxylate disodium salt | GENERAL ELECTRIC COMPANY | 2003-08-19 | — | — | US | disclosed |
| US-20030114633-A1 | Salts of heterocyclic diols as catalysts for melt polycarbonate | GENERAL ELECTRIC COMPANY | 2003-06-19 | — | — | US | disclosed |