Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299039 | 0.84 | TSHR (0.56) | TSHRHSD17B10CNR1LMNATP53 | |
| SCHEMBL11304640 | 0.82 | HSD17B10 (0.57) | TSHRHSD17B10CNR1LMNATP53 | |
| SCHEMBL11303345 | 0.78 | TSHR (0.57) | TSHRHSD17B10TP53RAB9AMAPT | |
| SCHEMBL23779608 | 0.77 | CNR2 (0.48) | TSHRLMNAALDH1A1CYP2D6 | |
| SCHEMBL11278172 | 0.77 | CNR2 (0.48) | TSHRLMNAALDH1A1CYP2D6 | |
| SCHEMBL11179622 | 0.76 | NPC1 (0.52) | TSHRHSD17B10LMNAMCHR1RAB9A | |
| SCHEMBL11200220 | 0.76 | POLB (0.54) | TSHRHSD17B10LMNATP53RAB9A | |
| SCHEMBL11196583 | 0.76 | MCHR1 (0.53) | TSHRHSD17B10CNR1LMNAMCHR1 | |
| SCHEMBL11165531 | 0.76 | MCHR1 (0.55) | TSHRHSD17B10CNR1LMNAMCHR1 | |
| SCHEMBL11165965 | 0.76 | MCHR1 (0.55) | TSHRHSD17B10CNR1LMNAMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |