Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690151 | 0.85 | AKR1C3 (0.69) | AKR1C3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL31668557 | 0.85 | AKR1C3 (0.69) | AKR1C3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28467269 | 0.83 | AKR1C3 (0.72) | AKR1C3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29701296 | 0.83 | AKR1C3 (1.00) | AKR1C3ALDH1A1KDM4EHSD17B10SRD5A2 | |
| SCHEMBL503364 | 0.83 | AKR1C3 (1.00) | AKR1C3ALDH1A1KDM4EHSD17B10SRD5A2 | |
| SCHEMBL28637350 | 0.81 | AKR1C3 (0.96) | AKR1C3ALDH1A1KDM4EHSD17B10SRD5A2 | |
| SCHEMBL8523127 | 0.80 | HNF4A (0.60) | AKR1C3ALDH1A1KDM4EHPGDSRD5A2 | |
| SCHEMBL14124717 | 0.79 | AKR1C3 (0.67) | AKR1C3ALDH1A1HSD17B10SRD5A2LMNA | |
| SCHEMBL28052811 | 0.79 | AKR1C3 (0.67) | AKR1C3ALDH1A1SRD5A2LMNAPOLB | |
| SCHEMBL28384877 | 0.79 | AKR1C3 (0.85) | AKR1C3ALDH1A1SRD5A2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259383-A | PEROXY COMPOUNDS | STERLING DRUG INC. (US) | 1981-03-31 | — | — | US | disclosed |