Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.41 |
| ▸ | FNTB | P49356 | 9/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305075 | 0.95 | KMT2A (0.39) | FNTAFNTBKDM1AKMT2AMAPT | |
| Benzoic Acid SCHEMBL11300062 | 0.86 | ICMT (0.39) | FNTAFNTBKDM1AMAPTTRPA1 | |
| SCHEMBL11305714 | 0.85 | KMT2A (0.53) | FNTAFNTBKMT2AMAPTMEN1 | |
| SCHEMBL11705342 | 0.85 | KMT2A (0.53) | FNTAFNTBKMT2AMAPTMEN1 | |
| SCHEMBL17363846 | 0.73 | KMT2A (0.43) | FNTAFNTBKDM1AKMT2AMAPT | |
| SCHEMBL17363847 | 0.73 | KMT2A (0.43) | FNTAFNTBKDM1AKMT2AMAPT | |
| SCHEMBL808086 | 0.72 | KMT2A (0.56) | FNTAFNTBKMT2AMAPTMEN1 | |
| SCHEMBL1617090 | 0.72 | KMT2A (0.56) | FNTAFNTBKMT2AMAPTMEN1 | |
| SCHEMBL1616971 | 0.72 | KMT2A (0.56) | FNTAFNTBKMT2AMAPTMEN1 | |
| SCHEMBL28140446 | 0.69 | KDM4E (0.37) | FNTAFNTBKDM1AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260551-A | ALIPHATIC OR AROMATIC ESTERS, ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1981-04-07 | — | — | US | claimed |