Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.30 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13830714 | 0.79 | GABRP (0.33) | TSHRGABRR1GABRPGABRDGABRA1 | |
| SCHEMBL30608468 | 0.65 | GSK3A (0.43) | — | |
| SCHEMBL30608466 | 0.65 | GSK3A (0.43) | — | |
| SCHEMBL27426329 | 0.64 | TSHR (0.32) | TSHRGABRR1GABRPGABRDGABRA1 | |
| SCHEMBL7568266 | 0.64 | — | — | |
| SCHEMBL2296442 | 0.63 | — | — | |
| SCHEMBL11430568 | 0.63 | FFAR3 (0.36) | TSHR | |
| SCHEMBL13140760 | 0.62 | TSHR (0.39) | ABATTSHRGABRR1SLC6A1SLC6A13 | |
| SCHEMBL21121534 | 0.61 | NOTUM (0.33) | TSHRGABRR1SLC6A1SLC6A13GABRP | |
| SCHEMBL6544012 | 0.60 | GABRP (0.33) | TSHRGABRR1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275184-A | HYDROSILATION OF POLYDIMETHYL SILOXANE | RHONE-POULENC INDUSTRIES (FR) | 1981-06-23 | — | — | US | disclosed |
| US-4213914-A | ADDITION-CONDENSATION COPOLYMERS | RHONE-POULENC INDUSTRIES (FR) | 1980-07-22 | — | — | US | disclosed |
| US-4147711-A | Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom | RHONE-POULENC INDUSTRIES (FR) | 1979-04-03 | — | — | US | disclosed |
| US-4088670-A | P-(DIMETHYLVINYLSILYL-METHOXY)-BENZOYL CHLORIDE FROM DIMETHYLVINYL-CHLOROMETHYLSILANE AND A P-HYDROXYBENZOIC ACID | RHONE-POULENC INDUSTRIES (FR) | 1978-05-09 | — | — | US | disclosed |
| US-3933745-A | Imide copolymers possessing hydroxyl groups | RHONE-POULENC S.A. (FR) | 1976-01-20 | — | — | US | disclosed |