Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11307749 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AAHRMEN1 | |
| SCHEMBL11258785 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AAHRMEN1 | |
| SCHEMBL11258791 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AAHRMEN1 | |
| SCHEMBL29955509 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AAHRMEN1 | |
| SCHEMBL11290866 | 0.83 | HTT (0.71) | RAB9AMEN1KMT2AHTTMAPT | |
| SCHEMBL11289450 | 0.82 | MTNR1A (0.38) | SMN1; SMN2NPC1RAB9AAHRKMT2A | |
| SCHEMBL11286575 | 0.82 | MTNR1A (0.38) | SMN1; SMN2NPC1RAB9AAHRKMT2A | |
| SCHEMBL4980566 | 0.82 | GAA (0.64) | SMN1; SMN2NPC1RAB9AAHRMEN1 | |
| SCHEMBL11546092 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AAHRMEN1 | |
| SCHEMBL4314263 | 0.79 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9AAHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046283-A2 | 4-Phenoxy-2-butene derivatives and their use as plant growth regulators | J.T. Baker Chemical Co. (US) | 1982-02-24 | — | — | EP | disclosed |