SCHEMBL11308151

SCHEMBL11308151

C=C(CCCC(C)C)C1CC=C(C)CC1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
ALDH1A1 P00352 2/20 0.36
ALOX15 P16050 2/20 0.36
CYP1B1 Q16678 1/20 0.36
TSHR P16473 1/20 0.32
TRPA1 O75762 1/20 0.32
CNR1 P21554 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
CHRNA7 P36544 1/20 0.30
STAT3 P40763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11289934 0.80 LMNA (0.61) LMNAALDH1A1ALOX15CYP1B1TSHR
SCHEMBL20608601 0.76 LMNA (0.65) LMNAALDH1A1ALOX15CYP1B1TSHR
SCHEMBL20610540 0.76 LMNA (0.65) LMNAALDH1A1ALOX15CYP1B1TSHR
SCHEMBL7133749 0.76 LMNA (0.65) LMNAALDH1A1ALOX15CYP1B1TSHR
SCHEMBL1245213 0.76 LMNA (0.65) LMNAALDH1A1ALOX15CYP1B1TSHR
SCHEMBL11734806 0.74 LMNA (0.62) LMNAALDH1A1ALOX15CYP1B1TSHR
SCHEMBL30835524 0.74
SCHEMBL11306496 0.73 LMNA (0.49) LMNAALDH1A1ALOX15CYP1B1TRPA1
Bisabolone SCHEMBL83913 0.73 LMNA (0.57) LMNAALDH1A1ALOX15CYP1B1TSHR
Bisabolone SCHEMBL83912 0.73 LMNA (0.57) LMNAALDH1A1ALOX15CYP1B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0007076-B1 DIHYDROBISABOLENES AND DIHYDROBISABOLOL, THEIR PREPARATION AND USE AS ODOROUS SUBSTANCES BASF Aktiengesellschaft (DE) 1981-04-15 EP claimed
EP-0007076-B1 DIHYDROBISABOLENES AND DIHYDROBISABOLOL, THEIR PREPARATION AND USE AS ODOROUS SUBSTANCES BASF Aktiengesellschaft (DE) 1981-04-15 EP disclosed
EP-0007076-A1 Dihydrobisabolenes and dihydrobisabolol, their preparation and use as odorous substances BASF Aktiengesellschaft (DE) 1980-01-23 EP disclosed