Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167553 | 0.83 | HTR2A (0.43) | ALDH1A1CYP3A4CA2L3MBTL1LMNA | |
| SCHEMBL29663716 | 0.82 | HTR2A (0.42) | ALDH1A1CYP3A4CA2L3MBTL1LMNA | |
| SCHEMBL30229492 | 0.82 | HTR2A (0.42) | ALDH1A1CYP3A4CA2L3MBTL1LMNA | |
| SCHEMBL29019756 | 0.81 | ALDH1A1 (0.51) | TSHRALDH1A1CYP3A4CA2L3MBTL1 | |
| SCHEMBL11312168 | 0.79 | ALDH1A1 (0.46) | TSHRALDH1A1CYP3A4MAPK1HSD17B10 | |
| SCHEMBL11315129 | 0.78 | CNR2 (0.41) | TSHRALDH1A1CYP3A4TP53ALOX15 | |
| SCHEMBL11310264 | 0.78 | ALDH1A1 (0.43) | TSHRALDH1A1CYP3A4CA2L3MBTL1 | |
| SCHEMBL11311115 | 0.77 | CNR2 (0.40) | TSHRALDH1A1CYP3A4TDP1TP53 | |
| SCHEMBL11322015 | 0.76 | ALDH1A1 (0.44) | TSHRALDH1A1CYP3A4MAPK1HSD17B10 | |
| SCHEMBL11312251 | 0.76 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257987-A | SYNERGISTIC ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-24 | — | — | US | disclosed |