Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304936 | 0.82 | TSHR (0.38) | TSHRTHRBSCDPTGS2ALDH1A1 | |
| SCHEMBL1480092 | 0.82 | TSHR (0.38) | TSHRTHRBSCDPTGS2ALDH1A1 | |
| SCHEMBL1176912 | 0.82 | TSHR (0.38) | TSHRTHRBSCDPTGS2ALDH1A1 | |
| SCHEMBL5597049 | 0.82 | TSHR (0.38) | TSHRTHRBSCDPTGS2ALDH1A1 | |
| SCHEMBL168713 | 0.82 | TSHR (0.38) | TSHRTHRBSCDPTGS2ALDH1A1 | |
| SCHEMBL242339 | 0.82 | TSHR (0.38) | TSHRTHRBSCDPTGS2ALDH1A1 | |
| SCHEMBL1777114 | 0.82 | TSHR (0.38) | TSHRTHRBSCDPTGS2ALDH1A1 | |
| SCHEMBL2868810 | 0.82 | TSHR (0.38) | TSHRTHRBSCDPTGS2ALDH1A1 | |
| SCHEMBL23854647 | 0.67 | TSHR (1.00) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Hexadecane SCHEMBL23499901 | 0.67 | TSHR (1.00) | TSHRTHRBALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |