SCHEMBL168713

SCHEMBL168713

CCCCCCCCCCC[C]1CCO1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
EPHX1 P07099 1/20 0.35
SCD O00767 1/20 0.35
PTGS2 P35354 3/20 0.34
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
ALDH1A1 P00352 2/20 0.34
KCNH2 Q12809 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
HSPD1 P10809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL242339 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL1777114 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL1176912 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL1480092 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL5597049 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL11304936 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL2868810 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL1383985 0.90
SCHEMBL459181 0.88 FAAH (0.44) TSHRALDH1A1
SCHEMBL10696277 0.86 MEN1 (0.34) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117961046-A Durable zirconium tundish nozzle and preparation method thereof 江苏泰瑞耐火有限公司 2024-05-03 CN claimed
CN-117845625-A One-step preparation method and application of temperature-regulating fabric 东华大学 2024-04-09 CN claimed
US-20240074956-A1 COSMETIC COMPOSITIONS, KITS THEREOF, AND METHODS FOR MAKING AND USING THE SAME L'OREAL (FR) 2024-03-07 US claimed
US-20240026192-A1 A WATER-DISPERSIBLE PRESSURE SENSITIVE ADHESIVE COMPOSITION ARKEMA FRANCE (FR) 2024-01-25 US claimed
CN-117206515-A Preparation method of submicron nano silver powder by low-temperature sintering 苏州星翰新材料科技有限公司 2023-12-12 CN claimed
US-11819560-B2 Cosmetic compositions, kits thereof, and methods for making and using the same L'OREAL (FR) 2023-11-21 US claimed
CN-116889890-A Catalyst system special for mild coal liquefaction with high conversion rate and mild coal liquefaction method 辽宁科技大学 2023-10-17 CN claimed
EP-4247910-A1 A WATER-DISPERSIBLE PRESSURE SENSITIVE ADHESIVE COMPOSITION ARKEMA FRANCE (FR) 2023-09-27 EP claimed
CN-116725260-A Protective clothing and preparation method and application thereof 张家港市泾东针织毛绒有限公司 2023-09-12 CN claimed
CN-116721795-A Method for preparing silver paste for photovoltaic cell by using high-conductivity flaky micron silver powder 苏州星翰新材料科技有限公司 2023-09-08 CN claimed
US-6207135-B1 BIODEGRADABLE WALL MATERIAL OF THE PARTICLES IS MADE FROM A BLEND OF LIQUID CRYSTALS BLOCK POLYMERS OF POLYLACTONES AND POLYOXYETHYLENE GLYCOL OR POLYLACTONES; CONTROLLED RETENTION TIME; CONTRAST OF BLOOD FLOW, ORGANS; NONTOXIC; ANTIALLERGENS INHALE THERAPEUTIC SYSTEMS, INC. 2001-03-27 US claimed
US-5759565-A DRUG FOR NASAL ADMINISTRATION NOVARTIS CORPORATION (US) 1998-06-02 US claimed
EP-0170529-B1 ANTISTATIC COMPOSITIONS COMPRISING POLYMERIZED OXYALKYLENE MONOMERS AND AN INORGANIC SALT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-04-15 EP claimed
US-5081100-A Stretched, crosslinked polyethylene thin film support MITSUBISHI PAPER MILLS LIMITED (JP) 1992-01-14 US claimed
CN-1013841-B MAGNETIC INK MEDIUM AND PRINTING METHOD USING MEDIUM SEIKO EPSON CORP (JP) 1991-09-11 CN claimed
US-4828799-A Therapeutic drug monitoring and analyte determination utilizing micellar chromatography RESEARCH CORPORATION (US) 1989-05-09 US claimed
EP-0107078-B1 POLYMERIZATION PROCESS FOR CARBOXYL CONTAINING POLYMERS The B.F. GOODRICH Company (US) 1986-10-01 EP claimed
EP-0107078-A1 Polymerization process for carboxyl containing polymers The B.F. GOODRICH Company (US) 1984-05-02 EP claimed
US-4419502-A METHYLENE CHLORIDE, NONIONIC SURFACTANT THE B. F. GOODRICH COMPANY (US) 1983-12-06 US claimed
EP-0006020-A1 Brominated rubbers and preparation thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1979-12-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074956-A1 COSMETIC COMPOSITIONS, KITS THEREOF, AND METHODS FOR MAKING AND USING THE SAME CUTA, LIPC, MGLL TSHR 4421/4885THRB 4564/4885EPHX1 2797/4885
US-11819560-B2 Cosmetic compositions, kits thereof, and methods for making and using the same CUTA, LIPC, MGLL TSHR 4421/4885THRB 4564/4885EPHX1 2797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.