Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312915 | 0.86 | PARP15 (0.46) | PARP15PARP10 | |
| SCHEMBL11312939 | 0.86 | PARP15 (0.46) | PARP15PARP10 | |
| SCHEMBL11316856 | 0.82 | PARP15 (0.43) | PARP15PARP10 | |
| SCHEMBL13110604 | 0.82 | PARP15 (0.43) | PARP15PARP10 | |
| SCHEMBL11316847 | 0.82 | PARP15 (0.43) | PARP15PARP10 | |
| SCHEMBL11310619 | 0.82 | SLC6A2 (0.69) | SLC6A2SLC6A4HTR3AKCNH2SLC6A3 | |
| SCHEMBL25289066 | 0.81 | CYP3A4 (0.57) | SLC6A2SLC6A4HTR3AKCNH2SLC6A3 | |
| SCHEMBL31140645 | 0.81 | CYP3A4 (0.57) | SLC6A2SLC6A4HTR3AKCNH2SLC6A3 | |
| SCHEMBL1758227 | 0.80 | PARP15 (0.51) | SLC6A2SLC6A4HTR3AKCNH2SLC6A3 | |
| SCHEMBL19908929 | 0.80 | LMNA (0.39) | SLC6A2SLC6A4KCNH2SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261651-A | CYCLOHEXANE CONTAINING DERIVATIVES OF AROMATIC NITRILES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1981-04-14 | — | — | US | disclosed |