Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.65 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | MB | P02144 | 1/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | RARG | P13631 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311425 | 0.96 | CACNA1B (0.69) | CACNA1BAPBA1MAPTALDH1A1MEN1 | |
| SCHEMBL13210697 | 0.85 | CACNA1B (0.85) | CACNA1BAPBA1MAPTALDH1A1MEN1 | |
| SCHEMBL22116992 | 0.83 | CACNA1B (0.54) | CACNA1BAPBA1MAPTALDH1A1MEN1 | |
| SCHEMBL29556024 | 0.83 | CACNA1B (0.54) | CACNA1BAPBA1MAPTALDH1A1MEN1 | |
| SCHEMBL11676225 | 0.82 | MEN1 (0.77) | CACNA1BAPBA1MAPTALDH1A1MEN1 | |
| SCHEMBL11413442 | 0.82 | MEN1 (0.77) | CACNA1BAPBA1MAPTALDH1A1MEN1 | |
| SCHEMBL14880210 | 0.82 | CACNA1B (0.67) | CACNA1BAPBA1MAPTALDH1A1MEN1 | |
| SCHEMBL10153970 | 0.82 | CACNA1B (0.67) | CACNA1BAPBA1MAPTALDH1A1MEN1 | |
| SCHEMBL11324085 | 0.80 | NPC1 (0.63) | CACNA1BAPBA1ALDH1A1CA1CA9 | |
| SCHEMBL13986883 | 0.80 | CACNA1B (0.76) | CACNA1BAPBA1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-3994987-A | Metal deactivators as adhesion promotors for vulcanizable elastomers to metals | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |