Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MB | P02144 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311425 | 0.86 | CACNA1B (0.69) | CACNA1BAPBA1MAPTCYP2C9ALDH1A1 | |
| SCHEMBL11310488 | 0.83 | CACNA1B (0.65) | CACNA1BAPBA1MAPTCYP2C9ALDH1A1 | |
| SCHEMBL31375577 | 0.80 | ALDH1A1 (0.70) | MAPTCYP2C9ALDH1A1MEN1KMT2A | |
| SCHEMBL29556024 | 0.77 | CACNA1B (0.54) | CACNA1BAPBA1MAPTCYP2C9ALDH1A1 | |
| SCHEMBL22116987 | 0.77 | CA1 (0.53) | MAPTALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL13210697 | 0.77 | CACNA1B (0.85) | CACNA1BAPBA1MAPTALDH1A1MEN1 | |
| SCHEMBL22117097 | 0.76 | MEN1 (0.53) | MAPTALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL28923985 | 0.76 | ALDH1A1 (0.44) | CYP2C9ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL22117042 | 0.75 | PLK1 (0.56) | MAPTCYP2C9ALDH1A1MEN1KMT2A | |
| SCHEMBL11676225 | 0.74 | MEN1 (0.77) | CACNA1BAPBA1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144815-A1 | 1,3,4-OXADIAZOLES AND THEIR DERIVATIVES AS NEW ANTIFUNGAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-12 | — | — | US | disclosed |
| WO-2021255093-A1 | ACTIVE COMPOUND COMBINATION | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-23 | — | — | WO | disclosed |
| EP-3897154-A1 | 1,3,4-OXADIAZOLES AND THEIR DERIVATIVES AS NEW ANTIFUNGAL AGENTS | Bayer Aktiengesellschaft (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020127974-A1 | 1,3,4-OXADIAZOLES AND THEIR DERIVATIVES AS NEW ANTIFUNGAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144815-A1 | 1,3,4-OXADIAZOLES AND THEIR DERIVATIVES AS NEW ANTIFUNGAL AGENTS | CYP51A1, ERG28, DPM1 | CACNA1B 3863/4885APBA1 3661/4885MAPT 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.