Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 7/20 | 0.44 |
| ▸ | WNT3A | P56704 | 11/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1130876 | 0.94 | IGF1R (0.43) | IGF1RWNT3APPARGPPARDPPARA | |
| SCHEMBL1130204 | 0.91 | WNT3A (0.49) | IGF1RWNT3APPARGPPARDPPARA | |
| SCHEMBL1130353 | 0.90 | IGF1R (0.45) | IGF1RWNT3APPARGPPARDPPARA | |
| SCHEMBL1130244 | 0.89 | IGF1R (0.48) | IGF1RWNT3APPARGPPARDPPARA | |
| SCHEMBL1129781 | 0.89 | IGF1R (0.48) | IGF1RWNT3APPARGPPARDPPARA | |
| SCHEMBL1131333 | 0.88 | WNT3A (0.48) | IGF1RWNT3A | |
| SCHEMBL1131275 | 0.88 | IGF1R (0.47) | IGF1RWNT3APPARGPPARDPPARA | |
| SCHEMBL1130012 | 0.88 | IGF1R (0.42) | IGF1RWNT3APPARGPPARDPPARA | |
| Trifluoroacetic Acid SCHEMBL1130315 | 0.88 | IGF1R (0.46) | IGF1RWNT3APPARGPPARDPPARA | |
| SCHEMBL1130676 | 0.88 | IGF1R (0.47) | IGF1RWNT3APPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773808-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2011-02-16 | — | — | EP | claimed |