Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.55 |
| ▸ | HTR3B | O95264 | 1/20 | 0.55 |
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.55 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311359 | 1.00 | MEN1 (0.56) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL11311356 | 1.00 | MEN1 (0.56) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL11321796 | 0.86 | CHRM4 (0.52) | MEN1KMT2ACHRM4CHRM3SLC18A3 | |
| SCHEMBL11321790 | 0.86 | CHRM4 (0.52) | MEN1KMT2ACHRM4CHRM3SLC18A3 | |
| SCHEMBL11321792 | 0.86 | CHRM4 (0.52) | MEN1KMT2ACHRM4CHRM3SLC18A3 | |
| SCHEMBL28593173 | 0.84 | CHRM4 (0.51) | MEN1KMT2ACHRM4CHRM3CHRM1 | |
| SCHEMBL1623587 | 0.82 | CHRNA7 (0.61) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL1623586 | 0.82 | CHRNA7 (0.61) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL11313992 | 0.77 | CHRM4 (0.44) | CHRM4CHRM3 | |
| SCHEMBL11313995 | 0.77 | CHRM4 (0.44) | CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248876-A | Piperidine derivatives | JOHN WYETH & BROTHER LTD. (GB) | 1981-02-03 | — | — | US | claimed |
| US-4248876-A | Piperidine derivatives | JOHN WYETH & BROTHER LTD. (GB) | 1981-02-03 | — | — | US | disclosed |