Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12262668 | 0.84 | GABRA1 (0.50) | GABRA1GABRB2ALDH1A1MAPTMGLL | |
| SCHEMBL27774934 | 0.82 | GABRA1 (0.48) | GABRA1GABRB2ALDH1A1MAPTMGLL | |
| SCHEMBL28088611 | 0.82 | GABRA1 (0.48) | GABRA1GABRB2ALDH1A1MAPTMGLL | |
| SCHEMBL3194195 | 0.82 | GABRA1 (0.48) | GABRA1GABRB2ALDH1A1MAPTMGLL | |
| Hydrogen Peroxide SCHEMBL11570368 | 0.79 | GABRA1 (0.50) | GABRA1GABRB2ALDH1A1MAPTGAA | |
| SCHEMBL20263105 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1MAPTHSD11B1 | |
| SCHEMBL10218791 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1MAPTKMT2A | |
| SCHEMBL29120477 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2ALDH1A1MAPTMGLL | |
| SCHEMBL18916830 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2ALDH1A1MAPTMGLL | |
| SCHEMBL16105766 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2ALDH1A1MAPTMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272446-A | KETALIZATION, HALOHYDRINATION | PIERREL S.P.A. (IT) | 1981-06-09 | — | — | US | disclosed |
| US-4226862-A | 2-BROMO-6BETA-FLUOROPREGNA-1,4-DIENE-3,20-DIONES, ANTIINFLAMMATORY AGENTS | PIERREL S.P.A. (IT) | 1980-10-07 | — | — | US | disclosed |