Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | ACR | P10323 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25438849 | 1.00 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2PRSS1ACRSRD5A2 | |
| SCHEMBL29993193 | 0.95 | HSD17B10 (0.64) | ALDH1A1SMN1; SMN2PRSS1ACRSRD5A2 | |
| SCHEMBL2741098 | 0.92 | PRSS1 (0.69) | ALDH1A1SMN1; SMN2PRSS1ACRHSD17B10 | |
| SCHEMBL9663961 | 0.92 | PRSS1 (0.69) | ALDH1A1SMN1; SMN2PRSS1ACRHSD17B10 | |
| SCHEMBL8929987 | 0.92 | PRSS1 (0.69) | ALDH1A1SMN1; SMN2PRSS1ACRHSD17B10 | |
| SCHEMBL8930157 | 0.92 | PRSS1 (0.69) | ALDH1A1SMN1; SMN2PRSS1ACRHSD17B10 | |
| SCHEMBL1101878 | 0.92 | PRSS1 (0.69) | ALDH1A1SMN1; SMN2PRSS1ACRHSD17B10 | |
| SCHEMBL4597931 | 0.90 | PARP10 (0.62) | ALDH1A1PRSS1ACRSRD5A2HSD17B10 | |
| SCHEMBL376498 | 0.90 | PARP10 (0.62) | ALDH1A1PRSS1ACRSRD5A2HSD17B10 | |
| SCHEMBL7536846 | 0.90 | PARP10 (0.62) | ALDH1A1PRSS1ACRSRD5A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017059942-A1 | CHIRAL COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-04-13 | — | — | WO | disclosed |
| WO-2017025167-A1 | MATERIAL COMBINATION | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | WO | disclosed |
| WO-2014169985-A1 | MESOGENIC COMPOUND, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | WO | disclosed |
| WO-2013156113-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2013-10-24 | — | — | WO | disclosed |
| US-8449953-B2 | Chiral dopants, liquid crystal matrix and manufacturing method thereof and liquid crystal display | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-05-28 | — | — | US | disclosed |
| WO-2013034219-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2013-03-14 | — | — | WO | disclosed |
| US-20130063693-A1 | CHIRAL DOPANTS, LIQUID CRYSTAL MATRIX AND MANUFACTURING METHOD THEREOF AND LIQUID CRYSTAL DISPLAY | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-03-14 | — | — | US | disclosed |
| US-7198827-B1 | Nematic liquid crystal composition and liquid crystal display device using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-04-03 | — | — | US | disclosed |
| US-4259383-A | PEROXY COMPOUNDS | STERLING DRUG INC. (US) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130063693-A1 | CHIRAL DOPANTS, LIQUID CRYSTAL MATRIX AND MANUFACTURING METHOD THEREOF AND LIQUID CRYSTAL DISPLAY | CNPY2, YBX3, CCR3 | ALDH1A1 3647/4885SMN1; SMN2 2173/4885PRSS1 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.