Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049380 | 0.79 | CYP2D6 (0.61) | CYP2D6CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL17583642 | 0.78 | L3MBTL1 (0.61) | KMT2ALMNAL3MBTL1PKMSCN5A | |
| SCHEMBL9721972 | 0.75 | CYP2D6 (0.74) | CYP2D6CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL12993016 | 0.74 | CYP2D6 (0.73) | CYP2D6CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL11887346 | 0.74 | CYP2D6 (0.79) | CYP2D6CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL10932466 | 0.73 | CYP2D6 (1.00) | CYP2D6CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL5167194 | 0.73 | CYP2D6 (0.64) | CYP2D6CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL14542581 | 0.73 | CYP2D6 (0.76) | CYP2D6CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL13381683 | 0.73 | CYP2D6 (0.76) | CYP2D6CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL10044464 | 0.72 | CYP2D6 (0.69) | CYP2D6CYP1A2CYP2C19KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282251-A | FUNGICIDES | SANDOZ LTD. (CH) | 1981-08-04 | — | — | US | disclosed |