Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009174 | 0.90 | ALDH1A1 (0.38) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL2326051 | 0.75 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL2325787 | 0.75 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL2325790 | 0.75 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL2325783 | 0.75 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL11316954 | 0.73 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL30913005 | 0.72 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL11122133 | 0.72 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL137825 | 0.71 | — | — | |
| SCHEMBL27865953 | 0.71 | MEN1 (0.41) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307112-A | 9-Deoxy-9A-methylene isosteres of PGI2 and process for their preparation | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-12-22 | — | — | US | disclosed |