Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11316045 | 0.93 | TSHR (0.47) | CYP3A4TSHRCYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL11306538 | 0.91 | CYP3A4 (0.46) | CYP3A4TSHRCYP2C19SMN1; SMN2IDO1 | |
| SCHEMBL11558847 | 0.84 | BLM (0.53) | CYP2C19SMN1; SMN2IDO1AGXTALDH1A1 | |
| SCHEMBL26048058 | 0.82 | CA1 (0.40) | CYP3A4TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL1413702 | 0.78 | SMN1; SMN2 (0.66) | CYP3A4TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL134443 | 0.76 | IDO1 (0.46) | TSHRIDO1AGXTAPP | |
| SCHEMBL1592157 | 0.75 | CYP3A4 (0.54) | CYP3A4TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL31270 | 0.75 | IDO1 (0.67) | CYP3A4TSHRSMN1; SMN2IDO1AGXT | |
| SCHEMBL6327626 | 0.75 | IDO1 (0.48) | IDO1AGXTAPP | |
| SCHEMBL9622317 | 0.75 | CYP3A4 (0.65) | CYP3A4TSHRALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248976-A | COMPRISING A PHOSPHORUS COMPOUND AND AN AROMATIC COMPOUND | CIBA-GEIGY AG (CH) | 1981-02-03 | — | — | US | disclosed |
| US-4172858-A | Flame-resistant polymer compositions | CIBA-GEIGY AG (CH) | 1979-10-30 | — | — | US | disclosed |
| US-4163731-A | HYDRAULIC FLUIDS | CIBA-GEIGY AG (CH) | 1979-08-07 | — | — | US | disclosed |